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Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

Plasmodium falciparum stage V gametocytes are responsible for parasite transmission, and drugs targeting this stage are needed to support malaria elimination. We here screen the Tres Cantos Antimalarial Set (TCAMS) using the previously developed P. falciparum female gametocyte activation assay (Pf F...

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Detalles Bibliográficos
Autores principales:	Miguel-Blanco, Celia, Molina, Irene, Bardera, Ana I., Díaz, Beatriz, de las Heras, Laura, Lozano, Sonia, González, Carolina, Rodrigues, Janneth, Delves, Michael J., Ruecker, Andrea, Colmenarejo, Gonzalo, Viera, Sara, Martínez-Martínez, María S., Fernández, Esther, Baum, Jake, Sinden, Robert E., Herreros, Esperanza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442318/ https://www.ncbi.nlm.nih.gov/pubmed/28513586 http://dx.doi.org/10.1038/ncomms15160

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