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Caspase-2-mediated cell death is required for deleting aneuploid cells
Caspase-2, one of the most evolutionarily conserved of the caspase family, has been implicated in maintenance of chromosomal stability and tumour suppression. Caspase-2 deficient (Casp2(−/−)) mice develop normally but show premature ageing-related traits and when challenged by certain stressors, suc...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442422/ https://www.ncbi.nlm.nih.gov/pubmed/27991927 http://dx.doi.org/10.1038/onc.2016.423 |