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Caspase-2-mediated cell death is required for deleting aneuploid cells

Caspase-2, one of the most evolutionarily conserved of the caspase family, has been implicated in maintenance of chromosomal stability and tumour suppression. Caspase-2 deficient (Casp2(−/−)) mice develop normally but show premature ageing-related traits and when challenged by certain stressors, suc...

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Detalles Bibliográficos
Autores principales:	Dawar, S, Lim, Y, Puccini, J, White, M, Thomas, P, Bouchier-Hayes, L, Green, D R, Dorstyn, L, Kumar, S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442422/ https://www.ncbi.nlm.nih.gov/pubmed/27991927 http://dx.doi.org/10.1038/onc.2016.423

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