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Infiltrating mast cells promote renal cell carcinoma angiogenesis by modulating PI3K→AKT→GSK3β→AM signaling

The recruitment of vascular endothelial cells from the tumor microenvironment (TME) to promote angiogenesis plays key roles in the progression of renal cell carcinoma (RCC). The potential impact of immune cells in the TME on RCC angiogenesis, however, remains unclear. Here, we found that recruitment...

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Detalles Bibliográficos
Autores principales: Chen, Y, Li, C, Xie, H, Fan, Y, Yang, Z, Ma, J, He, D, Li, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442425/
https://www.ncbi.nlm.nih.gov/pubmed/28114284
http://dx.doi.org/10.1038/onc.2016.442

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