Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression

Aneuploidy is usually deleterious in multicellular organisms but appears to be tolerated and potentially beneficial in unicellular organisms, including pathogens. Leishmania, a major protozoan parasite, is emerging as a new model for aneuploidy, since in vitro-cultivated strains are highly aneuploid...

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Detalles Bibliográficos
Autores principales: Dumetz, F., Imamura, H., Sanders, M., Seblova, V., Myskova, J., Pescher, P., Vanaerschot, M., Meehan, C. J., Cuypers, B., De Muylder, G., Späth, G. F., Bussotti, G., Vermeesch, J. R., Berriman, M., Cotton, J. A., Volf, P., Dujardin, J. C., Domagalska, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442457/
https://www.ncbi.nlm.nih.gov/pubmed/28536289
http://dx.doi.org/10.1128/mBio.00599-17

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