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Rational Redesign of a Functional Protein Kinase-Substrate Interaction

[Image: see text] Eukaryotic protein kinases typically phosphorylate substrates in the context of specific sequence motifs, contributing to specificity essential for accurate signal transmission. Protein kinases recognize their target sequences through complementary interactions within the active si...

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Detalles Bibliográficos
Autores principales:	Chen, Catherine, Nimlamool, Wutigri, Miller, Chad J., Lou, Hua Jane, Turk, Benjamin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442603/ https://www.ncbi.nlm.nih.gov/pubmed/28314095 http://dx.doi.org/10.1021/acschembio.7b00089

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