Cargando…

Protein‐Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's Disease

Transplantation of stem cells into the brain attenuates functional deficits in the central nervous system via cell replacement, the release of specific neurotransmitters, and the production of neurotrophic factors. To identify patient‐specific and safe stem cells for treating Alzheimer's diseas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cha, Moon‐Yong, Kwon, Yoo‐Wook, Ahn, Hyo‐Suk, Jeong, Hyobin, Lee, Yong Yook, Moon, Minho, Baik, Sung Hoon, Kim, Dong Kyu, Song, Hyundong, Yi, Eugene C., Hwang, Daehee, Kim, Hyo‐Soo, Mook‐Jung, Inhee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Translational Research Articles and Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442740/ https://www.ncbi.nlm.nih.gov/pubmed/28170178 http://dx.doi.org/10.5966/sctm.2016-0081

Ejemplares similares

The role of mitochondrial DNA mutation on neurodegenerative diseases
por: Cha, Moon-Yong, et al.
Publicado: (2015)

Synapsin-1 and tau reciprocal O-GlcNAcylation and phosphorylation sites in mouse brain synaptosomes
por: Kang, Min Jueng, et al.
Publicado: (2013)

Amyloid β‐induced elevation of O‐GlcNAcylated c‐Fos promotes neuronal cell death
por: Choi, Heesun, et al.
Publicado: (2018)

Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer’s disease
por: Song, Hyundong, et al.
Publicado: (2015)

Visualization of Altered Hippocampal Connectivity in an Animal Model of Alzheimer’s Disease
por: Jeon, Seong Gak, et al.
Publicado: (2018)

Nurr1 (NR4A2) regulates Alzheimer’s disease‐related pathogenesis and cognitive function in the 5XFAD mouse model
por: Moon, Minho, et al.
Publicado: (2018)

Close Correlation of Monoamine Oxidase Activity with Progress of Alzheimer’s Disease in Mice, Observed by in Vivo Two-Photon Imaging
por: Kim, Dokyoung, et al.
Publicado: (2016)

Aβ-induced mitochondrial dysfunction in neural progenitors controls KDM5A to influence neuronal differentiation
por: Kim, Dong Kyu, et al.
Publicado: (2022)

Phosphokinase Antibody Arrays on Dendron-Coated Surface
por: Kwak, Ju-Won, et al.
Publicado: (2014)

Disruption of blood-brain barrier in Alzheimer disease pathogenesis
por: Kook, Sun-Young, et al.
Publicado: (2013)

The Clinical Significance of Uric Acid Deposits
por: Campbell, F. R.
Publicado: (1887)

Accumulation of Phosphorylated β-Catenin Enhances ROS-Induced Cell Death in Presenilin-Deficient Cells
por: Boo, Jung H., et al.
Publicado: (2009)

Imprinted gene Zinc finger protein 127 is a novel regulator of master pluripotency transcription factor, Oct4
por: Kwon, Yoo-Wook, et al.
Publicado: (2018)

The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer’s disease pathogenesis
por: Kim, Yoonhee, et al.
Publicado: (2016)

p53-dependent SIRT6 expression protects Aβ42-induced DNA damage
por: Jung, Eun Sun, et al.
Publicado: (2016)

Acquisition of pluripotency in the chick embryo occurs during intrauterine embryonic development via a unique transcriptional network
por: Han, Jae Yong, et al.
Publicado: (2018)

Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice
por: Jeon, Seong Gak, et al.
Publicado: (2018)

The role of cell type-specific mitochondrial dysfunction in the pathogenesis of Alzheimer’s disease
por: Kim, Dong Kyu, et al.
Publicado: (2019)

Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer’s disease
por: Kim, Dong Kyu, et al.
Publicado: (2019)

Disruption of Sorting Nexin 5 Causes Respiratory Failure Associated with Undifferentiated Alveolar Epithelial Type I Cells in Mice
por: Im, Sun-Kyoung, et al.
Publicado: (2013)

P-Glycoprotein Induction Ameliorates Colistin Induced Nephrotoxicity in Cultured Human Proximal Tubular Cells
por: Lee, Sun-hyo, et al.
Publicado: (2015)

Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death
por: Cha, Moon-Yong, et al.
Publicado: (2012)

Formation of yttria-stabilized zirconia nanotubes by atomic layer deposition toward efficient solid electrolytes
por: Kim, Eunsoo, et al.
Publicado: (2017)

Clinical applications of patient-specific induced pluripotent stem cells in cardiovascular medicine
por: Oh, Yingzi, et al.
Publicado: (2012)

The appearance of C1q deposition in transplanted kidney allografts and its clinical and histopathologic features
por: Jo, Eun-Ah, et al.
Publicado: (2022)

ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer
por: Jun, Ikhyun, et al.
Publicado: (2017)

Advance of Thrombolysis and Thrombectomy in Acute Ischemic Stroke
por: Nam, Hyo Suk, et al.
Publicado: (2023)

β‐Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreas
por: Kim, Hyo‐Sup, et al.
Publicado: (2016)

Modeling Catecholaminergic Polymorphic Ventricular Tachycardia using Induced Pluripotent Stem Cell-derived Cardiomyocytes
por: Novak, Atara, et al.
Publicado: (2012)

Heat stress-induced memory impairment is associated with neuroinflammation in mice
por: Lee, Wonil, et al.
Publicado: (2015)

Altered APP Processing in Insulin-Resistant Conditions Is Mediated by Autophagosome Accumulation via the Inhibition of Mammalian Target of Rapamycin Pathway
por: Son, Sung Min, et al.
Publicado: (2012)

Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions
por: Son, Sung Min, et al.
Publicado: (2012)

Expression of pluripotency-related genes in human glioblastoma
por: Rios, Álvaro Fabrício Lopes, et al.
Publicado: (2021)

Red Ginseng Inhibits Tau Aggregation and Promotes Tau Dissociation In Vitro
por: Shin, Soo Jung, et al.
Publicado: (2020)

Special issue on neurodegenerative diseases and their therapeutic approaches
por: Kim, Jungsu, et al.
Publicado: (2015)

PRAK mediates Aβ-RAGE driven autophagy pathway
por: Kim, Yoonhee, et al.
Publicado: (2017)

Low Ankle-Brachial Index Is Associated With Stroke Recurrence in Ischemic Stroke Patients With Atrial Fibrillation
por: Han, Minho, et al.
Publicado: (2021)

Impact of interankle blood pressure difference on major adverse cardiovascular events in cryptogenic stroke patients without peripheral artery disease: a retrospective cohort study
por: Han, Minho, et al.
Publicado: (2022)

Intratumoral Photodynamic Therapy With Newly Synthesized Pheophorbide a in Murine Oral Cancer
por: Ahn, Mee-Young, et al.
Publicado: (2017)

Everolimus Rescues the Phenotype of Elastin Insufficiency in Patient Induced Pluripotent Stem Cell–Derived Vascular Smooth Muscle Cells
por: Kinnear, Caroline, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_us2887ahge1fksm8i7oa3uu3nf