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Enhanced Immunosuppression of T Cells by Sustained Presentation of Bioactive Interferon‐γ Within Three‐Dimensional Mesenchymal Stem Cell Constructs

The immunomodulatory activity of mesenchymal stem/stromal cells (MSCs) to suppress innate and adaptive immune responses offers a potent cell therapy for modulating inflammation and promoting tissue regeneration. However, the inflammatory cytokine milieu plays a critical role in stimulating MSC immun...

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Detalles Bibliográficos
Autores principales:	Zimmermann, Joshua A., Hettiaratchi, Marian H., McDevitt, Todd C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Translational Research Articles and Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442746/ https://www.ncbi.nlm.nih.gov/pubmed/28170190 http://dx.doi.org/10.5966/sctm.2016-0044

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