Cargando…

The Cleavage Effect of Mesenchymal Stem Cell and Its Derived Matrix Metalloproteinase‐2 on Extracellular α‐Synuclein Aggregates in Parkinsonian Models

Ample evidence has suggested that extracellular α‐synuclein aggregates would play key roles in the pathogenesis and progression of Parkinsonian disorders (PDs). In the present study, we investigated whether mesenchymal stem cells (MSCs) and their derived soluble factors could exert neuroprotective e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oh, Se Hee, Kim, Ha Na, Park, Hyun Jung, Shin, Jin Young, Kim, Dong Yeol, Lee, Phil Hyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Translational Research Articles and Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442774/ https://www.ncbi.nlm.nih.gov/pubmed/28297586 http://dx.doi.org/10.5966/sctm.2016-0111

Ejemplares similares

Priming mesenchymal stem cells with α-synuclein enhances neuroprotective properties through induction of autophagy in Parkinsonian models
por: Shin, Jin Young, et al.
Publicado: (2022)

Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models
por: Kim, Ha Na, et al.
Publicado: (2021)

Feasibility and Efficacy of Intra‐Arterial Administration of Mesenchymal Stem Cells in an Animal Model of Double Toxin‐Induced Multiple System Atrophy
por: Na Kim, Ha, et al.
Publicado: (2017)

Uric acid regulates α-synuclein transmission in Parkinsonian models
por: Shin, Yu Jin, et al.
Publicado: (2023)

Uric Acid Enhances Neurogenesis in a Parkinsonian Model by Remodeling Mitochondria
por: Lee, Ji Eun, et al.
Publicado: (2022)

Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery
por: Nam, Hyo Suk, et al.
Publicado: (2015)

Clinical Implications of Cardiac-MIBG SPECT in the Differentiation of Parkinsonian Syndromes
por: Shin, Dong Hoon, et al.
Publicado: (2006)

Correction: Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery
por: Nam, Hyo Suk, et al.
Publicado: (2016)

Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage
por: Jobin, Parker G., et al.
Publicado: (2020)

Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer
por: Korpi, J T, et al.
Publicado: (2008)

Chronic carbon disulfide exposure induces parkinsonian pathology via α-synuclein aggregation and necrosome complex interaction
por: Liu, Zhidan, et al.
Publicado: (2023)

Dopamine, Alpha-Synuclein, and Mitochondrial Dysfunctions in Parkinsonian Eyes
por: Indrieri, Alessia, et al.
Publicado: (2020)

Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients
por: Yin (殷晓科), Xiaoke, et al.
Publicado: (2019)

Mesenchymal stem cells stabilize the blood–brain barrier through regulation of astrocytes
por: Park, Hyun Jung, et al.
Publicado: (2015)

Changes in matrix protein biochemistry and the expression of mRNA encoding matrix proteins and metalloproteinases in posterior tibialis tendinopathy
por: Corps, Anthony N, et al.
Publicado: (2012)

Elevated Homocysteine by Levodopa Is Detrimental to Neurogenesis in Parkinsonian Model
por: Shin, Jin Young, et al.
Publicado: (2012)

The (Extracellular) Matrix Reloaded: Imaging Matrix Metalloproteinase Activity
por: Lillis, Kyle P.
Publicado: (2021)

Tumor Immunotherapy Using Gene-Modified Human Mesenchymal Stem Cells Loaded into Synthetic Extracellular Matrix Scaffolds
por: Compte, Marta, et al.
Publicado: (2009)

T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy
por: Haj-Shomaly, Jozafina, et al.
Publicado: (2022)

Evaluation of α‐synuclein in CNS‐originating extracellular vesicles for Parkinsonian disorders: A systematic review and meta‐analysis
por: Taha, Hash Brown, et al.
Publicado: (2023)

Production and activity of matrix metalloproteinases during liver fibrosis progression of chronic hepatitis C patients
por: Martinez-Castillo, Moises, et al.
Publicado: (2021)

Obesity Blunts the Effect of Mesenchymal Stem Cell-Derived Extracellular Vesicles
por: Huang, Weijun, et al.
Publicado: (2023)

Computational design of Matrix Metalloproteinase-9 (MMP-9) resistant to auto-cleavage
por: Bonadio, Alessandro, et al.
Publicado: (2023)

Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
por: Croisier, Emilie, et al.
Publicado: (2005)

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
por: Bandopadhyay, Rina
Publicado: (2016)

Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases
por: Genovese, Federica, et al.
Publicado: (2013)

Cleavage/Alteration of Interleukin-8 by Matrix Metalloproteinase-9 in the Female Lower Genital Tract
por: Zariffard, M. Reza, et al.
Publicado: (2015)

Association and prognostic significance of alpha-L-fucosidase-1 and matrix metalloproteinase 9 expression in esophageal squamous cell carcinoma
por: Yu, Xiang-Yang, et al.
Publicado: (2022)

Targeting extracellular matrix remodeling sensitizes glioblastoma to ionizing radiation
por: Thakur, Varsha, et al.
Publicado: (2022)

Correction: Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
por: Croisier, Emilie, et al.
Publicado: (2006)

A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix deposition
por: Schiffmann, L M, et al.
Publicado: (2017)

Matrix Metalloproteinases and Glaucoma
por: Kim, Moo Hyun, et al.
Publicado: (2022)

Extracellular matrix degradation by host matrix metalloproteinases in restorative dentistry and endodontics: An overview
por: Anshida, V P, et al.
Publicado: (2020)

Matrix metalloproteinase-induced cervical extracellular matrix remodelling in pregnancy and cervical cancer
por: Amabebe, Emmanuel, et al.
Publicado: (2022)

Effects of matrix metalloproteinases on the fate of mesenchymal stem cells
por: Almalki, Sami G., et al.
Publicado: (2016)

Effect of advanced glycation end products, extracellular matrix metalloproteinase inducer and matrix metalloproteinases on type-I collagen metabolism
por: LI, WANG, et al.
Publicado: (2016)

Variable Surface Glycoprotein from Trypanosoma brucei Undergoes Cleavage by Matrix Metalloproteinases: An in silico Approach
por: Moreno, Cláudia Jassica Gonçalves, et al.
Publicado: (2019)

Sequestration of synaptic proteins by alpha-synuclein aggregates leading to neurotoxicity is inhibited by small peptide
por: Choi, Mal-Gi, et al.
Publicado: (2018)

Extracellular matrix metalloproteinase inducer in brain ischemia and intracerebral hemorrhage
por: Liu, Yang, et al.
Publicado: (2022)

Extracellular matrix metalloproteinase inducer as a biomarker for oral cancer
por: Katariya, Chanchal, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1nru3f139dbo0lauh9npamu5vp