A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing

The development of targeted therapeutics for rare neurodevelopmental disorders (NDDs) faces significant challenges due to the scarcity of subjects and the difficulty of obtaining human neural cells. Here, we illustrate a rapid, simple protocol by which patient derived cells can be reprogrammed to in...

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Detalles Bibliográficos
Autores principales: Bell, Scott, Peng, Huashan, Crapper, Liam, Kolobova, Ilaria, Maussion, Gilles, Vasuta, Cristina, Yerko, Volodymyr, Wong, Tak Pan, Ernst, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Translational Research Articles and Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442775/
https://www.ncbi.nlm.nih.gov/pubmed/28170165
http://dx.doi.org/10.1002/sctm.16-0158

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