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Generation of Human Induced Pluripotent Stem Cell‐Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy

Allogeneic fetal‐derived human neural stem cells (hfNSCs) that are under clinical evaluation for several neurodegenerative diseases display a favorable safety profile, but require immunosuppression upon transplantation in patients. Neural progenitors derived from patient‐specific induced pluripotent...

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Detalles Bibliográficos
Autores principales: Meneghini, Vasco, Frati, Giacomo, Sala, Davide, De Cicco, Silvia, Luciani, Marco, Cavazzin, Chiara, Paulis, Marianna, Mentzen, Wieslawa, Morena, Francesco, Giannelli, Serena, Sanvito, Francesca, Villa, Anna, Bulfone, Alessandro, Broccoli, Vania, Martino, Sabata, Gritti, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442804/
https://www.ncbi.nlm.nih.gov/pubmed/28191778
http://dx.doi.org/10.5966/sctm.2015-0414