Microfluidic Screening Reveals Heparan Sulfate Enhances Human Mesenchymal Stem Cell Growth by Modulating Fibroblast Growth Factor‐2 Transport

Cost‐effective expansion of human mesenchymal stem/stromal cells (hMSCs) remains a key challenge for their widespread clinical deployment. Fibroblast growth factor‐2 (FGF‐2) is a key hMSC mitogen often supplemented to increase hMSC growth rates. However, hMSCs also produce endogenous FGF‐2, which cr...

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Detalles Bibliográficos
Autores principales: Titmarsh, Drew M., Tan, Clarissa L.L., Glass, Nick R., Nurcombe, Victor, Cooper‐White, Justin J., Cool, Simon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Translational Research Articles and Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442852/
https://www.ncbi.nlm.nih.gov/pubmed/28205415
http://dx.doi.org/10.1002/sctm.16-0343

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