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DMD transcripts in CRL-2061 rhabdomyosarcoma cells show high levels of intron retention by intron-specific PCR amplification

BACKGROUND: The DMD gene encoding dystrophin is mutated in Duchenne muscular dystrophy, a fatal progressive muscle wasting disease. DMD has also been shown to act as a tumor suppressor gene. Rhabdomyosarcoma (RMS) is a mesodermal sarcoma that shares characteristics of skeletal muscle precursors. Pro...

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Detalles Bibliográficos
Autores principales:	Niba, Emma Tabe Eko, Yamanaka, Ryo, Rani, Abdul Qawee Mahyoob, Awano, Hiroyuki, Matsumoto, Masaaki, Nishio, Hisahide, Matsuo, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442858/ https://www.ncbi.nlm.nih.gov/pubmed/28546788 http://dx.doi.org/10.1186/s12935-017-0428-4

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