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Pepsinogen C expression, regulation and its relationship with cancer

Pepsinogen C (PGC) belongs to the aspartic protease family and is secreted by gastric chief cells. PGC could be activated to pepsin C and digests polypeptides and amino acids, but as a zymogen PGC’s functions is unclear. In normal physiological conditions, PGC is initially detected in the late embry...

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Detalles Bibliográficos
Autores principales: Shen, Shixuan, Jiang, Jingyi, Yuan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442862/
https://www.ncbi.nlm.nih.gov/pubmed/28546787
http://dx.doi.org/10.1186/s12935-017-0426-6