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Dissecting microsatellite instability in colorectal cancer: one size does not fit all
Microsatellite instability (MSI) marks distinct subsets of tumors in many cancer types and is caused by mutations in genes required for mismatch repair. A recent report analyses the molecular foundations of MSI-positive colorectal cancers and reveals substantial molecular heterogeneity, which might...
Autores principales: | Samstein, Robert M., Chan, Timothy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442871/ https://www.ncbi.nlm.nih.gov/pubmed/28539127 http://dx.doi.org/10.1186/s13073-017-0438-9 |
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