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Pharmacokinetic and Pharmacodynamic Efficacies of Continuous versus Intermittent Administration of Meropenem in Patients with Severe Sepsis and Septic Shock: A Prospective Randomized Pilot Study
BACKGROUND: The antibiotic meropenem is commonly administered in patients with severe sepsis and septic shock. We compared the pharmacokinetic, clinical, and bacteriological efficacies of continuous infusion of meropenem versus intermittent administration in such patients. METHODS: Patients admitted...
Autores principales: | Zhao, Hui-Ying, Gu, Jian, Lyu, Jie, Liu, Dan, Wang, Yi-Tong, Liu, Fang, Zhu, Feng-Xue, An, You-Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443018/ https://www.ncbi.nlm.nih.gov/pubmed/28485312 http://dx.doi.org/10.4103/0366-6999.205859 |
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