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Lipopolysaccharide Stimulates Surfactant Protein-A in Human Renal Epithelial HK-2 Cells through Upregulating Toll-like Receptor 4 Dependent MEK1/2-ERK1/2-NF-κB Pathway
BACKGROUND: Surfactant protein-A (SP-A) contributes to the regulation of sepsis-induced acute kidney injury. In a previous study, we demonstrated that the expression of SP-A in the human renal tubular epithelial (HK-2) cells can be stimulated by lipopolysaccharide (LPS). The present study evaluated...
Autores principales: | Liu, Jiao, Li, Guang, Xie, Wen-Jie, Wang, Lu, Zhang, Rui, Huang, Ke-Sheng, Zhou, Qing-Shan, Chen, De-Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443031/ https://www.ncbi.nlm.nih.gov/pubmed/28485325 http://dx.doi.org/10.4103/0366-6999.205853 |
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