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Lipopolysaccharide Stimulates Surfactant Protein-A in Human Renal Epithelial HK-2 Cells through Upregulating Toll-like Receptor 4 Dependent MEK1/2-ERK1/2-NF-κB Pathway

BACKGROUND: Surfactant protein-A (SP-A) contributes to the regulation of sepsis-induced acute kidney injury. In a previous study, we demonstrated that the expression of SP-A in the human renal tubular epithelial (HK-2) cells can be stimulated by lipopolysaccharide (LPS). The present study evaluated...

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Detalles Bibliográficos
Autores principales: Liu, Jiao, Li, Guang, Xie, Wen-Jie, Wang, Lu, Zhang, Rui, Huang, Ke-Sheng, Zhou, Qing-Shan, Chen, De-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443031/
https://www.ncbi.nlm.nih.gov/pubmed/28485325
http://dx.doi.org/10.4103/0366-6999.205853

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