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Artesunate influences Th17/Treg lymphocyte balance by modulating Treg apoptosis and Th17 proliferation in a murine model of rheumatoid arthritis
CD4(+) regulatory T (Treg) cells and T-helper 17 (Th17) cells have been shown to have important roles in rheumatoid arthritis (RA). In our previous study, it was demonstrated that artesunate was able to alter the Treg/Th17 ratio in patients with RA; however, the underlying mechanisms remain unclear....
Autores principales: | Liu, Jia, Hong, Xuezhi, Lin, Dong, Luo, Xiaohong, Zhu, Mengya, Mo, Hanyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443220/ https://www.ncbi.nlm.nih.gov/pubmed/28565837 http://dx.doi.org/10.3892/etm.2017.4232 |
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