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Recombinant Bacille Calmette-Guérin coexpressing Ag85B-IFN-γ enhances the cell-mediated immunity in C57BL/6 mice

The only available vaccine against pulmonary tuberculosis is Bacille Calmette-Guérin (BCG). As the efficacy reported of the vaccine is not up to the mark, there is an urgent need to develop improved anti-tuberculosis vaccines. Antigen 85B (Ag85B) is a very promising vaccine candidate molecule of Myc...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Xu, Ying, Shen, Hongbo, Yan, Jingran, Yang, Enzhuo, Wang, Honghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443280/
https://www.ncbi.nlm.nih.gov/pubmed/28565847
http://dx.doi.org/10.3892/etm.2017.4273