Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin

Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications o...

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Detalles Bibliográficos
Autores principales: Bukreyeva, Iryna, Angoulvant, Adela, Bendib, Inès, Gagnard, Jean-Charles, Bourhis, Jean-Henri, Dargère, Sylvie, Bonhomme, Julie, Thellier, Marc, Gachot, Bertrand, Wyplosz, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443440/
https://www.ncbi.nlm.nih.gov/pubmed/28518017
http://dx.doi.org/10.3201/eid2306.161825
Descripción
Sumario:Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly.

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