Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin

Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications o...

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Autores principales: Bukreyeva, Iryna, Angoulvant, Adela, Bendib, Inès, Gagnard, Jean-Charles, Bourhis, Jean-Henri, Dargère, Sylvie, Bonhomme, Julie, Thellier, Marc, Gachot, Bertrand, Wyplosz, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443440/
https://www.ncbi.nlm.nih.gov/pubmed/28518017
http://dx.doi.org/10.3201/eid2306.161825
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author Bukreyeva, Iryna
Angoulvant, Adela
Bendib, Inès
Gagnard, Jean-Charles
Bourhis, Jean-Henri
Dargère, Sylvie
Bonhomme, Julie
Thellier, Marc
Gachot, Bertrand
Wyplosz, Benjamin
author_facet Bukreyeva, Iryna
Angoulvant, Adela
Bendib, Inès
Gagnard, Jean-Charles
Bourhis, Jean-Henri
Dargère, Sylvie
Bonhomme, Julie
Thellier, Marc
Gachot, Bertrand
Wyplosz, Benjamin
author_sort Bukreyeva, Iryna
collection PubMed
description Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly.
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spelling pubmed-54434402017-06-02 Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin Bukreyeva, Iryna Angoulvant, Adela Bendib, Inès Gagnard, Jean-Charles Bourhis, Jean-Henri Dargère, Sylvie Bonhomme, Julie Thellier, Marc Gachot, Bertrand Wyplosz, Benjamin Emerg Infect Dis Research Letter Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly. Centers for Disease Control and Prevention 2017-06 /pmc/articles/PMC5443440/ /pubmed/28518017 http://dx.doi.org/10.3201/eid2306.161825 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Bukreyeva, Iryna
Angoulvant, Adela
Bendib, Inès
Gagnard, Jean-Charles
Bourhis, Jean-Henri
Dargère, Sylvie
Bonhomme, Julie
Thellier, Marc
Gachot, Bertrand
Wyplosz, Benjamin
Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_full Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_fullStr Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_full_unstemmed Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_short Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_sort enterocytozoon bieneusi microsporidiosis in stem cell transplant recipients treated with fumagillin
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443440/
https://www.ncbi.nlm.nih.gov/pubmed/28518017
http://dx.doi.org/10.3201/eid2306.161825
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