Domestic Pig Unlikely Reservoir for MERS-CoV

We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause disease, but a low level of virus replication, shedding, and seroconversion were observed. Pigs do not recapitulate human MERS-CoV and are unlikel...

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Detalles Bibliográficos
Autores principales: de Wit, Emmie, Feldmann, Friederike, Horne, Eva, Martellaro, Cynthia, Haddock, Elaine, Bushmaker, Trenton, Rosenke, Kyle, Okumura, Atsushi, Rosenke, Rebecca, Saturday, Greg, Scott, Dana, Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443456/
https://www.ncbi.nlm.nih.gov/pubmed/28318484
http://dx.doi.org/10.3201/eid2306.170096
Descripción
Sumario:We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause disease, but a low level of virus replication, shedding, and seroconversion were observed. Pigs do not recapitulate human MERS-CoV and are unlikely to constitute a reservoir in nature.

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