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Stress-induced release of Oct-1 from the nuclear envelope is mediated by JNK phosphorylation of lamin B1
The nuclear lamina can bind and sequester transcription factors (TFs), a function lost if the lamina is abnormal, with missing or mutant lamin proteins. We now show that TF sequestration is not all-or-nothing, but a dynamic physiological response to external signals. We show that the binding of the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443517/ https://www.ncbi.nlm.nih.gov/pubmed/28542436 http://dx.doi.org/10.1371/journal.pone.0177990 |