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Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse
BACKGROUND: During pregnancy, the mammary glands from Id2 mutant animals are deficient in lobulo-alveolar development. This failure of development is believed to be due to a proliferation defect. METHODS: We have asked whether functional Id2 expression is necessary for Wnt induced mammary hyperplasi...
Autores principales: | Marino, Susan, Romelfanger, Claire, Yokota, Yoshifumi, Nusse, Roel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544352/ https://www.ncbi.nlm.nih.gov/pubmed/15601467 http://dx.doi.org/10.1186/1471-2407-4-91 |
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