CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair

The repair of DNA double-strand breaks (DSBs) is mediated via two major pathways, nonhomologous end joining (NHEJ) and homologous recombination (HR) repair. DSB repair is vital for cell survival, genome stability, and tumor suppression. In contrast to NHEJ, HR relies on extensive homology and templa...

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Detalles Bibliográficos
Autores principales: Hilmi, Khalid, Jangal, Maïka, Marques, Maud, Zhao, Tiejun, Saad, Amine, Zhang, Chenxi, Luo, Vincent M., Syme, Alasdair, Rejon, Carlis, Yu, Zhenbao, Krum, Asiev, Fabian, Marc R., Richard, Stéphane, Alaoui-Jamali, Moulay, Orthwein, Alexander, McCaffrey, Luke, Witcher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443639/
https://www.ncbi.nlm.nih.gov/pubmed/28560323
http://dx.doi.org/10.1126/sciadv.1601898

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