A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication

G-quadruplexes (G4s) are nucleic acids secondary structures, epigenetic regulators in cells and viruses. In herpes simplex virus 1 (HSV-1)-infected cells, G4s are massively present during viral replication. We here aimed at investigating the possibility to target the HSV-1 G4s by a core extended nap...

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Detalles Bibliográficos
Autores principales: Callegaro, Sara, Perrone, Rosalba, Scalabrin, Matteo, Doria, Filippo, Palù, Giorgio, Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443766/
https://www.ncbi.nlm.nih.gov/pubmed/28539620
http://dx.doi.org/10.1038/s41598-017-02667-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443766/
https://www.ncbi.nlm.nih.gov/pubmed/28539620
http://dx.doi.org/10.1038/s41598-017-02667-3

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