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Prostaglandin E(2) glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y(6)

Cyclooxygenase-2 catalyses the biosynthesis of prostaglandins from arachidonic acid but also the biosynthesis of prostaglandin glycerol esters (PG-Gs) from 2-arachidonoylglycerol. Previous studies identified PG-Gs as signalling molecules involved in inflammation. Thus, the glyceryl ester of prostagl...

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Detalles Bibliográficos
Autores principales: Brüser, Antje, Zimmermann, Anne, Crews, Brenda C., Sliwoski, Gregory, Meiler, Jens, König, Gabriele M., Kostenis, Evi, Lede, Vera, Marnett, Lawrence J., Schöneberg, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443783/
https://www.ncbi.nlm.nih.gov/pubmed/28539604
http://dx.doi.org/10.1038/s41598-017-02414-8