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Prostaglandin E(2) glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y(6)
Cyclooxygenase-2 catalyses the biosynthesis of prostaglandins from arachidonic acid but also the biosynthesis of prostaglandin glycerol esters (PG-Gs) from 2-arachidonoylglycerol. Previous studies identified PG-Gs as signalling molecules involved in inflammation. Thus, the glyceryl ester of prostagl...
Autores principales: | Brüser, Antje, Zimmermann, Anne, Crews, Brenda C., Sliwoski, Gregory, Meiler, Jens, König, Gabriele M., Kostenis, Evi, Lede, Vera, Marnett, Lawrence J., Schöneberg, Torsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443783/ https://www.ncbi.nlm.nih.gov/pubmed/28539604 http://dx.doi.org/10.1038/s41598-017-02414-8 |
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