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Cooperation of Oncolytic Herpes Virotherapy and PD-1 Blockade in Murine Rhabdomyosarcoma Models
Oncolytic virotherapy is an effective immunotherapeutic approach for cancer treatment via a multistep process including direct tumor cell lysis, induction of cytotoxic or apoptosis-sensitizing cytokines and promotion of antitumor T cell responses. Solid tumors limit the effectiveness of immunotherap...
Autores principales: | Chen, Chun-Yu, Wang, Pin-Yi, Hutzen, Brian, Sprague, Les, Swain, Hayley M., Love, Julia K., Stanek, Joseph R., Boon, Louis, Conner, Joe, Cripe, Timothy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443787/ https://www.ncbi.nlm.nih.gov/pubmed/28539588 http://dx.doi.org/10.1038/s41598-017-02503-8 |
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