Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate

In this article newly synthesized azide derivative of hemin and DNA-hemin conjugate are characterized. Hemin-azide was purified using HPLC and characterized using elemental analysis, IR and NMR. The DNA-hemin conjugate was obtained via click chemistry [1] and click reaction was carried out using tra...

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Autores principales: Kosman, J., Stanislawska, A., Gluszynska, A., Juskowiak, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443925/
https://www.ncbi.nlm.nih.gov/pubmed/28560283
http://dx.doi.org/10.1016/j.dib.2017.05.020
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author Kosman, J.
Stanislawska, A.
Gluszynska, A.
Juskowiak, B.
author_facet Kosman, J.
Stanislawska, A.
Gluszynska, A.
Juskowiak, B.
author_sort Kosman, J.
collection PubMed
description In this article newly synthesized azide derivative of hemin and DNA-hemin conjugate are characterized. Hemin-azide was purified using HPLC and characterized using elemental analysis, IR and NMR. The DNA-hemin conjugate was obtained via click chemistry [1] and click reaction was carried out using traditional Cu-catalyzed and Cu-free approaches. The final product was successfully obtained using Cu-free cycloaddition. The identity of product was confirmed using Maldi TOF spectrometry. Obtained hemin-DNA conjugate exhibited peroxidase-like activity.
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spelling pubmed-54439252017-05-30 Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate Kosman, J. Stanislawska, A. Gluszynska, A. Juskowiak, B. Data Brief Data Article In this article newly synthesized azide derivative of hemin and DNA-hemin conjugate are characterized. Hemin-azide was purified using HPLC and characterized using elemental analysis, IR and NMR. The DNA-hemin conjugate was obtained via click chemistry [1] and click reaction was carried out using traditional Cu-catalyzed and Cu-free approaches. The final product was successfully obtained using Cu-free cycloaddition. The identity of product was confirmed using Maldi TOF spectrometry. Obtained hemin-DNA conjugate exhibited peroxidase-like activity. Elsevier 2017-05-13 /pmc/articles/PMC5443925/ /pubmed/28560283 http://dx.doi.org/10.1016/j.dib.2017.05.020 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Kosman, J.
Stanislawska, A.
Gluszynska, A.
Juskowiak, B.
Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate
title Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate
title_full Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate
title_fullStr Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate
title_full_unstemmed Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate
title_short Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate
title_sort dataset on characterization of hemin-azide derivative and dna oligonucleotide-hemin conjugate
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443925/
https://www.ncbi.nlm.nih.gov/pubmed/28560283
http://dx.doi.org/10.1016/j.dib.2017.05.020
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