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Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer’s disease

BACKGROUND: Rapid advancement of next generation sequencing technologies such as whole genome sequencing (WGS) has facilitated the search for genetic factors that influence disease risk in the field of human genetics. To identify rare variants associated with human diseases or traits, an efficient g...

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Detalles Bibliográficos
Autores principales:	Kim, Dokyoon, Basile, Anna O., Bang, Lisa, Horgusluoglu, Emrin, Lee, Seunggeun, Ritchie, Marylyn D., Saykin, Andrew J., Nho, Kwangsik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444041/ https://www.ncbi.nlm.nih.gov/pubmed/28539126 http://dx.doi.org/10.1186/s12911-017-0454-0

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