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FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue

OBJECTIVE: Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates metabolic homeostasis. Previous work has suggested that impairment of FGF21 signaling in adipose tissue may occur through downregulation of the obligate FGF21 co-receptor, β-klotho, which leads to “FGF21 resistance...

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Detalles Bibliográficos
Autores principales:	Markan, Kathleen R., Naber, Meghan C., Small, Sarah M., Peltekian, Lila, Kessler, Rachel L., Potthoff, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444074/ https://www.ncbi.nlm.nih.gov/pubmed/28580290 http://dx.doi.org/10.1016/j.molmet.2017.03.009

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