Hepatic gene therapy rescues high-fat diet responses in circadian Clock mutant mice

OBJECTIVE: Circadian Clock gene mutant mice show dampened 24-h feeding rhythms and an increased sensitivity to high-fat diet (HFD) feeding. Restricting HFD access to the dark phase counteracts its obesogenic effect in wild-type mice. The extent to which altered feeding rhythms are causative for the...

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Detalles Bibliográficos
Autores principales: Meyer-Kovac, Judit, Kolbe, Isa, Ehrhardt, Lea, Leliavski, Alexei, Husse, Jana, Salinas, Gabriela, Lingner, Thomas, Tsang, Anthony H., Barclay, Johanna L., Oster, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444075/
https://www.ncbi.nlm.nih.gov/pubmed/28580282
http://dx.doi.org/10.1016/j.molmet.2017.03.008

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