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Life expectancy difference and life expectancy ratio: two measures of treatment effects in randomised trials with non-proportional hazards
The hazard ratio (HR) is the most common measure of treatment effect in clinical trials that use time-to-event outcomes such as survival. When survival curves cross over or separate only after a considerable time, the proportional hazards assumption of the Cox model is violated, and HR can be mislea...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BMJ Publishing Group Ltd.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444092/ https://www.ncbi.nlm.nih.gov/pubmed/28546261 http://dx.doi.org/10.1136/bmj.j2250 |