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Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development
OBJECTIVE: Poor fetal nutrition increases the risk of type 2 diabetes in the offspring at least in part by reduced embryonic β-cell growth and impaired function. However, it is not entirely clear how fetal nutrients and growth factors impact β-cells during development to alter glucose homeostasis an...
Autores principales: | Elghazi, Lynda, Blandino-Rosano, Manuel, Alejandro, Emilyn, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444096/ https://www.ncbi.nlm.nih.gov/pubmed/28580286 http://dx.doi.org/10.1016/j.molmet.2017.03.010 |
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