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Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes
BACKGROUND: Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone. Therefore, here we set out to identify and characterize intrin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444103/ https://www.ncbi.nlm.nih.gov/pubmed/28545587 http://dx.doi.org/10.1186/s13073-017-0432-2 |