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Executive Function Improvement in Normal Pressure Hydrocephalus Following Shunt Surgery

The aim of this investigation was to evaluate improvement of executive functions after shunt surgery in patients with early normal pressure hydrocephalus (NPH). Patients with NPH were assessed before and after shunt surgery with tests shown to be sensitive to damage to the prefrontal cortex (PFC). S...

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Autores principales: Gleichgerrcht, Ezequiel, Cervio, Andrés, Salvat, Jorge, Loffredo, Anselmo Rodríguez, Vita, Luciana, Roca, María, Torralva, Teresa, Manes, Facundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444271/
https://www.ncbi.nlm.nih.gov/pubmed/19996515
http://dx.doi.org/10.3233/BEN-2009-0249
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author Gleichgerrcht, Ezequiel
Cervio, Andrés
Salvat, Jorge
Loffredo, Anselmo Rodríguez
Vita, Luciana
Roca, María
Torralva, Teresa
Manes, Facundo
author_facet Gleichgerrcht, Ezequiel
Cervio, Andrés
Salvat, Jorge
Loffredo, Anselmo Rodríguez
Vita, Luciana
Roca, María
Torralva, Teresa
Manes, Facundo
author_sort Gleichgerrcht, Ezequiel
collection PubMed
description The aim of this investigation was to evaluate improvement of executive functions after shunt surgery in patients with early normal pressure hydrocephalus (NPH). Patients with NPH were assessed before and after shunt surgery with tests shown to be sensitive to damage to the prefrontal cortex (PFC). Significant differences were found between basal and follow-up performances on the Boston Naming Test, the backwards digits span, Part B of the Trail Making Test, and the number of words produced on the phonological fluency task. In conclusion, our study reveals that patients with NPH who respond positively to continuous slow lumbar cerebral spinal fluid drainage and receive a ventriculoperitoneal shunt implant, improve their performance on tasks of executive function. Due to the high demand for this form of mental processing in real-life complex scenarios, and based on the severe executive deficits present in both demented and non-demented NPH patients, we encourage the assessment of executive functions in this clinical group.
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spelling pubmed-54442712017-06-05 Executive Function Improvement in Normal Pressure Hydrocephalus Following Shunt Surgery Gleichgerrcht, Ezequiel Cervio, Andrés Salvat, Jorge Loffredo, Anselmo Rodríguez Vita, Luciana Roca, María Torralva, Teresa Manes, Facundo Behav Neurol Research Article The aim of this investigation was to evaluate improvement of executive functions after shunt surgery in patients with early normal pressure hydrocephalus (NPH). Patients with NPH were assessed before and after shunt surgery with tests shown to be sensitive to damage to the prefrontal cortex (PFC). Significant differences were found between basal and follow-up performances on the Boston Naming Test, the backwards digits span, Part B of the Trail Making Test, and the number of words produced on the phonological fluency task. In conclusion, our study reveals that patients with NPH who respond positively to continuous slow lumbar cerebral spinal fluid drainage and receive a ventriculoperitoneal shunt implant, improve their performance on tasks of executive function. Due to the high demand for this form of mental processing in real-life complex scenarios, and based on the severe executive deficits present in both demented and non-demented NPH patients, we encourage the assessment of executive functions in this clinical group. IOS Press 2009 2009-12-07 /pmc/articles/PMC5444271/ /pubmed/19996515 http://dx.doi.org/10.3233/BEN-2009-0249 Text en Copyright © 2009 Hindawi Publishing Corporation and the authors. http://creativecommons.org/licenses/by/3.0 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Gleichgerrcht, Ezequiel
Cervio, Andrés
Salvat, Jorge
Loffredo, Anselmo Rodríguez
Vita, Luciana
Roca, María
Torralva, Teresa
Manes, Facundo
Executive Function Improvement in Normal Pressure Hydrocephalus Following Shunt Surgery
title Executive Function Improvement in Normal Pressure Hydrocephalus Following Shunt Surgery
title_full Executive Function Improvement in Normal Pressure Hydrocephalus Following Shunt Surgery
title_fullStr Executive Function Improvement in Normal Pressure Hydrocephalus Following Shunt Surgery
title_full_unstemmed Executive Function Improvement in Normal Pressure Hydrocephalus Following Shunt Surgery
title_short Executive Function Improvement in Normal Pressure Hydrocephalus Following Shunt Surgery
title_sort executive function improvement in normal pressure hydrocephalus following shunt surgery
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444271/
https://www.ncbi.nlm.nih.gov/pubmed/19996515
http://dx.doi.org/10.3233/BEN-2009-0249
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