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Impact of Chromosomal Rearrangement upon DNA Methylation Patterns in Leukemia

Genomic instability, including genetic mutations and chromosomal rearrangements, can lead to cancer development. Aberrant DNA methylation occurs commonly in cancer cells. The aim of this study is to determine the effects of a specific chromosomal lesion the BCR-ABL translocation t(9:22), in establis...

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Detalles Bibliográficos
Autores principales:	Byun, Hyang-Min, Eshaghian, Shahrooz, Douer, Dan, Trent, Jonathen, Garcia-Manero, Guillermo, Bhatia, Ravi, Siegmund, Kim, Yang, Allen S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter Open 2017
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444343/ https://www.ncbi.nlm.nih.gov/pubmed/28730166 http://dx.doi.org/10.1515/med-2017-0014

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