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Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose–Induced Apoptosis

PURPOSE: To investigate the effect of reducing high glucose (HG)-induced lysyl oxidase (LOX) overexpression and increased activity on retinal endothelial cell apoptosis. METHODS: Rat retinal endothelial cells (RRECs) were grown in normal (N) or HG (30 mM glucose) medium for 7 days. In parallel, RREC...

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Detalles Bibliográficos
Autores principales:	Kim, Dongjoon, Mecham, Robert P., Trackman, Philip C., Roy, Sayon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444550/ https://www.ncbi.nlm.nih.gov/pubmed/28538980 http://dx.doi.org/10.1167/iovs.16-21340

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