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The role of Aspartyl aminopeptidase (Ape4) in Cryptococcus neoformans virulence and authophagy
In order to survive and cause disease, microbial pathogens must be able to proliferate at the temperature of their infected host. We identified novel microbial features associated with thermotolerance in the opportunistic fungal pathogen Cryptococcus neoformans using a random insertional mutagenesis...
Autores principales: | Gontijo, Fabiano de Assis, de Melo, Amanda Teixeira, Pascon, Renata C., Fernandes, Larissa, Paes, Hugo Costa, Alspaugh, J. Andrew, Vallim, Marcelo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444613/ https://www.ncbi.nlm.nih.gov/pubmed/28542452 http://dx.doi.org/10.1371/journal.pone.0177461 |
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