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Adiponectin attenuates high glucose-induced apoptosis through the AMPK/p38 MAPK signaling pathway in NRK-52E cells

Excessive apoptosis of proximal tubule cell is closely related to the development of diabetes. Recent evidence suggests that adiponectin (ADPN) protects cells from high glucose induced apoptosis. However, the precise mechanisms remain poorly understood. We sought to investigate the role of p38 mitog...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Zhang, Juan, Zhang, Lian, Gao, Ping, Wu, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444659/
https://www.ncbi.nlm.nih.gov/pubmed/28542560
http://dx.doi.org/10.1371/journal.pone.0178215