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PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features

Previous studies have linked increased frequency of glycosylphosphatidylinositol-anchor protein (GPI-AP) deficiency with genomic instability and the risk of carcinogenesis. However, the underlying mechanism is still not clear. A randomForest analysis of the gene expression array data from 55 MDS pat...

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Detalles Bibliográficos
Autores principales: Teye, Emmanuel K., Sido, Abigail, Xin, Ping, Finnberg, Niklas K., Gokare, Prashanth, Kawasawa, Yuka I., Salzberg, Anna C., Shimko, Sara, Bayerl, Michael, Ehmann, W. Christopher, Claxton, David F., Rybka, Witold B., Drabick, Joseph J., Wang, Hong-Gang, Abraham, Thomas, El-Deiry, Wafik S., Brodsky, Robert A., Hohl, Raymond J., Pu, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444711/
https://www.ncbi.nlm.nih.gov/pubmed/28187452
http://dx.doi.org/10.18632/oncotarget.15136

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