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PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features
Previous studies have linked increased frequency of glycosylphosphatidylinositol-anchor protein (GPI-AP) deficiency with genomic instability and the risk of carcinogenesis. However, the underlying mechanism is still not clear. A randomForest analysis of the gene expression array data from 55 MDS pat...
Autores principales: | Teye, Emmanuel K., Sido, Abigail, Xin, Ping, Finnberg, Niklas K., Gokare, Prashanth, Kawasawa, Yuka I., Salzberg, Anna C., Shimko, Sara, Bayerl, Michael, Ehmann, W. Christopher, Claxton, David F., Rybka, Witold B., Drabick, Joseph J., Wang, Hong-Gang, Abraham, Thomas, El-Deiry, Wafik S., Brodsky, Robert A., Hohl, Raymond J., Pu, Jeffrey J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444711/ https://www.ncbi.nlm.nih.gov/pubmed/28187452 http://dx.doi.org/10.18632/oncotarget.15136 |
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