MiR-766 induces p53 accumulation and G2/M arrest by directly targeting MDM4

p53, a transcription factor that participates in multiple cellular functions, is considered the most important tumor suppressor. Previous evidence suggests that post-transcriptional deregulation of p53 by microRNAs contributes to tumorigenesis, tumor progression and therapeutic resistance. In the pr...

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Detalles Bibliográficos
Autores principales: Wang, Qingqing, Selth, Luke A., Callen, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444713/
https://www.ncbi.nlm.nih.gov/pubmed/28430625
http://dx.doi.org/10.18632/oncotarget.15530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444713/
https://www.ncbi.nlm.nih.gov/pubmed/28430625
http://dx.doi.org/10.18632/oncotarget.15530

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