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MiR-766 induces p53 accumulation and G2/M arrest by directly targeting MDM4

p53, a transcription factor that participates in multiple cellular functions, is considered the most important tumor suppressor. Previous evidence suggests that post-transcriptional deregulation of p53 by microRNAs contributes to tumorigenesis, tumor progression and therapeutic resistance. In the pr...

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Detalles Bibliográficos
Autores principales:	Wang, Qingqing, Selth, Luke A., Callen, David F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444713/ https://www.ncbi.nlm.nih.gov/pubmed/28430625 http://dx.doi.org/10.18632/oncotarget.15530

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