Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset

New approaches are needed for the treatment of patients with T-cell acute lymphoblastic leukemia (T-ALL) who fail to achieve remission with chemotherapy. Analysis of the effects of pan-PIM protein kinase inhibitors on human T-ALL cell lines demonstrated that the sensitive cell lines expressed higher...

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Detalles Bibliográficos
Autores principales: Padi, Sathish K.R., Luevano, Libia A., An, Ningfei, Pandey, Ritu, Singh, Neha, Song, Jin H., Aster, Jon C., Yu, Xue-Zhong, Mehrotra, Shikhar, Kraft, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444737/
https://www.ncbi.nlm.nih.gov/pubmed/28415816
http://dx.doi.org/10.18632/oncotarget.16320

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