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Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells
Programmed cell death ligand 1 (PD-L1) is a transmembrane protein that is expressed on tumor cells that suppresses the T cell-mediated immune response. Therapies targeting the PD-L1 pathway promote anti-tumor immunity and have shown promising results in some types of cancers. However, the functional...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444742/ https://www.ncbi.nlm.nih.gov/pubmed/28415820 http://dx.doi.org/10.18632/oncotarget.16326 |