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The histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells

The lysine demethylase 3A (KDM3A, JMJD1A or JHDM2A) controls transcriptional networks in a variety of biological processes such as spermatogenesis, metabolism, stem cell activity, and tumor progression. We matched transcriptomic and ChIP-Seq profiles to decipher a genome-wide regulatory network of e...

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Detalles Bibliográficos
Autores principales: Wilson, Stephen, Fan, Lingling, Sahgal, Natasha, Qi, Jianfei, Filipp, Fabian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444746/
https://www.ncbi.nlm.nih.gov/pubmed/28416760
http://dx.doi.org/10.18632/oncotarget.15681