Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer

Epidemiological studies have shown obesity to be linked with poorer outcomes in breast cancer patients. The molecular mechanisms responsible for the increased risk of invasive/metastatic disease with obesity are complex, but may include elevated levels of adipokines such as leptin. Using physiologic...

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Detalles Bibliográficos
Autores principales: Mishra, Ameet K., Parish, Christopher R., Wong, Ma-Li, Licinio, Julio, Blackburn, Anneke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444832/
https://www.ncbi.nlm.nih.gov/pubmed/28542577
http://dx.doi.org/10.1371/journal.pone.0178454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444832/
https://www.ncbi.nlm.nih.gov/pubmed/28542577
http://dx.doi.org/10.1371/journal.pone.0178454

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