SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2

Activation of SIRT1 has previously been shown to protect mice against osteoporosis through yet ill-defined mechanisms. In this study, we outline a role for SIRT1 as a positive regulator of the master osteoblast transcription factor, RUNX2. We find that ex vivo deletion of sirt1 leads to decreased ex...

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Detalles Bibliográficos
Autores principales: Zainabadi, Kayvan, Liu, Cassie J., Guarente, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444833/
https://www.ncbi.nlm.nih.gov/pubmed/28542607
http://dx.doi.org/10.1371/journal.pone.0178520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444833/
https://www.ncbi.nlm.nih.gov/pubmed/28542607
http://dx.doi.org/10.1371/journal.pone.0178520

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