Cargando…
SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2
Activation of SIRT1 has previously been shown to protect mice against osteoporosis through yet ill-defined mechanisms. In this study, we outline a role for SIRT1 as a positive regulator of the master osteoblast transcription factor, RUNX2. We find that ex vivo deletion of sirt1 leads to decreased ex...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444833/ https://www.ncbi.nlm.nih.gov/pubmed/28542607 http://dx.doi.org/10.1371/journal.pone.0178520 |